Department of Medical Microbiology and parasitology

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Browsing Department of Medical Microbiology and parasitology by Subject "Ampc"

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    Open Access
    Emergence of beta-lactamases OXA-10, VEB-1 and CMY in Providencia spp. from Nigeria
    (2011-05-24) Aibinu, I.E.; Pfeifer, Y.; Ogunsola, F.T.; Odugbemi, T.; Koenig, W.; Ghebremedhin, B.
    Resistance to cephalosporins of the third and fourth generations inEnterobacteriaceae is an increasing problem worldwide. This resist-ance is mainly attributed to the production of extended-spectrumb-lactamases (ESBLs). In Nigeria SHV-, TEM- and CTX-M-typeESBLs have been reported inEnterobacterspp.,Klebsiellaspp. andEscherichia coli.1–3Besides these classical ESBLs, there are variousother plasmid-mediatedb-lactamases that are less common butwhich are regarded as emerging and increasing in frequencyamong theb-lactamase family. Here we report the emergence ofOXA-10, VEB-1 and CMYb-lactamases and mobile genetic elementsin three clinical isolates ofProvidenciaspp. isolated between October2008 and April 2009 in two tertiary hospitals in Nigeria.