Cord blood haemoglobin and ferritin concentrations in newborns of anaemic and non‐anaemic mothers in Lagos, Nigeria
Date
2013
Authors
Adediran, A
Gbadegesin, A
Adeyemo, T.A
Akinbami, A
Osunkalu, V
Ogbenna, A.A
Akanmu, A.S
Journal Title
Journal ISSN
Volume Title
Publisher
Nigerian Medical Journal
Abstract
Background: Pre‐delivery haemoglobin and serum ferritin concentrations of anaemic and
non‐anaemic mothers were determined, and cord blood haemoglobin and serum ferritin
concentrations of their newborns were compared. This is to establish the mean values for
pre‐delivery haemoglobin and serum ferritin concentrations of anaemic and non‐anaemic
mothers and the cord blood haemoglobin and serum ferritin concentrations of their newborns
at term. Materials and Methods: A case–control study was done involving 142 pregnant
women and their newborns. They were divided into two groups – the anaemic group (n = 65)
and the non‐anaemic (n = 77) group. Five millilitres of blood was collected from each woman
and 2 ml was collected from the cord of their newborns into ethylenediaminetetraacetic
acid (EDTA) bottle and plain bottle for full blood count analysis and ferritin assay, respectively.
Results: The mean pre‐delivery haemoglobin concentrations of the women in anaemic group
and non‐anaemic group were 9.5 ± 1.01 g/dl and 12.15 ± 1.07 g/dl, respectively, and their mean
serum ferritin concentrations were 64.45 ± 138.76 μg/l and 32.83 ± 35.36 μg/l, respectively. The
mean cord blood haemoglobin concentrations for anaemic and for non‐anaemic groups were
12.54 ± 2.54 g/dl and 13.44 ± 2.23 g/dl (P = 0.02), respectively, and the mean cord blood serum
ferritin concentrations (non‐anaemic, 69.38 ± 78.88 μg/l; anaemic, 7.26 ± 115.60 μg/l)(P = 0.00)
were higher in the newborns of non‐anaemic than of anaemic mothers. Significant association
was found between maternal anaemia and cord blood ferritin concentrations (P = 0.025).
Conclusion: Maternal anaemia has significant effects on cord blood haemoglobin and serum
ferritin concentrations.
Description
Scholarly articles
Keywords
Anaemia , haemoglobin , newborn babies , pregnant women , serum ferritin , Research Subject Categories::MEDICINE
Citation
Adediran, A., Gbadegesin, A., Adeyemo, T.A., Akinbami, A., Osunkalu, V., Ogbenna, A.A. and Akanmu, A.S. (2013). Cord blood haemoglobin and ferritin concentrations in newborns of anaemic and non‐anaemic mothers in Lagos, Nigeria. Nigerian Medical Journal, 54(1), 22-26