Department of Anatomic and Molecular Pathology
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Enteromyeloschisis. A rare sacro - Enteric mass in the newborn
(Journal of Pediatric Surgery Case Reports, 2020-11)Introduction A lumbosacral appendage in a newborn is a source of extreme anxiety for parents. While sacral masses are the most common solid tumours of the newborn (1 in 20–45,000 live births), true caudal appendages (human ... -
Morphological Pattern of Childhood Solid Tumours in Lagos University Teaching Hospital.
(Nigerian Quarterly Journal of Hospital Medicine, 2009)Background: There is a wide variation in the incidence of childhood tumors world wide. The relative incidence of childhood tumors in developing countries is increasing and might add significantly to the high childhood ... -
EFFECT OF BRIDELIA FERRUGUBEA STEM BARK ON BLOOD CHEMISTRY AND HISTOLOGY OF SOME ORGANS IN RATS
(Nigerian Journal of Natural Products and Medicine, 1998)Aqueous extract of Bridelia ferruginea stem bark caused significant increases in serum K+, creatinine, total bilirubin, GOT, GPT, HDL, Alkaline phosphate, BUN (p<0.001) and decreases in serum Na+, Cl-, CO2), cholesterol, ... -
Prognostic factors in the management outcome of carcinoma of the larynx in Lagos.
(Nigerian Postgraduate Medical Journal, 2003)This is a retrospective analysis on the prognostic factors in the management outcome of clinically and histologically diagnosed carcinoma of larynx seen in Lagos University Teaching Hospital between 1996-1999. Various ... -
The Association Between Cancer Of The Breast And The Abo And Rhesus D Antigen Phenotypes In Lagos, Nigeria; A Case-Control Study
(Nigerian Journal of Clinical Practice, 2002)Objective: To determine whether inheritance of ABO and Rhesus D antigen phenotypes constitute a risk factor for development of cancer of the breast. Design: A case-control study. Setting: Patients with histologically ... -
Endometrial Carcinoma Following Treatment for Breast Carcinoma in a Nigerian Female. A Case Report and Review of the Literature
(Nigerian Postgraduate Medical Journal, 2017)Tamoxifen is the primary hormonal therapy for breast cancer as well as its chemoprevention. It is used in the management of breast cancer because of its anti oestrogenic effect. It is however an agonist on the endometrium ... -
Recurrence of anti-GBM Antibody Disease Twelve Years After Transplantation Associated With De Novo IgA Nephropathy
(Clinical nephrology, 1998)A patient developed recurrent anti-glomerular basement membrane (GBM) antibody (ab) disease after twelve years of an uneventful posttransplant course, clinically accompanied by rapidly rising creatinine. He additionally ... -
Adhesion molecules and rejection of renal allografts
(Kidney international, 1997)Adhesion molecules and rejection of renal allografts. Despite an increasing amount of immunohistochemical and molecular biology data relating to the pathogenesis of kidney transplant rejection, the pathological diagnosis ... -
Rising incidence of cerebral malaria in Lagos, Nigeria: a postmoterm study.
(East African Medical Journal, 1993)One hundred and forty seven cases of acute malaria were diagnosed at autopsy between 1988 and 1991 at the Lagos University Teaching Hospital (LUTH). In 67 (46.5%) cases death was attributed to cerebral malaria (CM). There ... -
Overexpression of p53 in Nigerian breast cancers and its relationship with tumour grade and oestrogen /progesterone expressions
(Orient Journal of Medicine, 2015)Background: Mutation of the tumour suppressor gene, p53, is implicated in most cancers. This gene has also been associated with high tumour grade in breast cancers. African women are known to generally have high grade ... -
Female malignant breast lesions: the Lagos University Teaching Hospital experience (1999–2013)
(Nigerian Quarterly Journal of Hospital Medicine, 2016)Background: Breast cancer is the most common cancer in women worldwide and its incidence has been on the increase. Nigeria is no exception to this trend. Objectives: The aim of this study is to review malignant breast ... -
Extremity Soft Tissue Sarcoma: A Review of 19 Cases.
(Nigerian Journal of Orthopaedics and Trauma, 2007)Background: Although soft tissue sarcoma is a rare tumour, it accounts for a significant proportion of malignancies seen in many orthopaedic practices. The objectives of this study are to evaluate the pattern of presentation ... -
Juvenile polyposis syndrome presenting as intussusception in a malnourished child: a case report
(Nigerian Journal of Gastroenterology and Hepatology, 2017)We report a rare case of juvenile polyposis syndrome (JPS) in a 5 year old girl who was admitted into the emergency room on account of acute intestinal obstruction secondary to ileo-colic intussusception. Prior to the ... -
Invasive Cribriform Carcinoma of the Male Breast
(Annals of Tropical Pathology, 2019)Male breast cancer is rare and it accounts for about 1 % of all breast cancers. Men of African and Jewish descent have higher risk of developing breast cancer. Invasive cribriform carcinoma of the breast, which has a good ... -
Derivation of a List of Priority Antibodies from the Analysis of a Cohort of Cases sent from Nigeria for External Consultation
(Annals of Tropical Pathology, 2017)Introduction: The major obstacle to developing sustainable services in a resource-limited setting, which hitherto has not had routine availability of diagnostic immunohistochemistry (IHC), is choosing from a large array ... -
Pathological Services in Sub-Saharan Africa, a Barrier to Effective Cancer Care
(Springer Cham, 2017)Cancer constitutes a significant public health burden in developing countries where more than 50% of new cases of cancers occurring worldwide are seen. In most of these less developed nations, sterling quality pathology ... -
Perioperative Haemorrhage and Transfusion in Musculoskeletal Tumour Surgery.
(Nigeria Journal of Orthopaedics and Trauma, 2008)Abstract Background and Objectives: Musculoskeletal tumor surgery in the West African subregion is rapidly evolving. These procedures are associated with significant blood losses necessitating large amount of transfusion, ... -
Management of Giant Cell Tumour: A Nigerian Experience
(Nigerian Journal of Surgical Sciences, 2007)Giant cell tumours (GCT) are the commonest bone tumours worldwide. It is rarely malignant but when it does it progresses to fibrosarcoma with high mortality. Otherwise it causes poor cosmesis, disability and pathological ... -
Well Differentiated Neuroendocrine Carcinoma of the Testis in a Nigerian Male
(JOURNAL OF CASE REPORTS, 2015)Testicular carcinoids are very rare tumors that account for less than 1% of all testicular neoplasms. We present the first case of a testicular carcinoid tumor in a Nigerian male who had radical orchiectomy on account of ... -
Pattern of Osteochondromas in Lagos, Nigeria
(Nigerian Quarterly Journal Hospital of Medicine, 2008)Osteochondromas are the most common benign tumours of bone. It is a problem of rapidly growing skeleton. Most of them are asymptomatic. The most common reason for presentation being perception of the lesion as a cosmetic ...