A point prevalence survey of antimicrobial prescribing in four nigerian tertiary hospitals
Date
2017
Authors
Oduyebo, O.O.
Olayinka, A.T.
Iregbu, K.C.
Versporten, A.
Goossens, H.
Nwajiobi-princewill, P.I.
Jimoh, O.
Ige, T.O.
Aigbe, A.I.
Ola-bello, O.I.
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters kluwer - medknow42
Abstract
Antimicrobial resistance has become a global challenge in health care. Its emergence in previously sensitive bacteria is usually associated with poor antibiotic-prescribing patterns. Methodology: A point prevalence survey was carried out in four tertiary hospitals in Nigeria in 2015 to determine the rate and characteristics of antibiotic prescription. Results: Of 828 patients eligible for the study, 69.7% received antibiotics, with highest rates in the adult Intensive Care Unit. There were therapeutic indications in 51.2% of the prescriptions, of which 89.5% were for community-acquired infections. Third-generation cephalosporins were the most prescribed antibiotics. On the evaluation of surgical prophylaxis, only 4.1% were compliant with institutional guidelines and 39.2% gave a reason for prescribing in patient case notes. Less than 1% of the prescriptions were based on the use of biomarkers. Conclusion: The prevalence of antibiotic prescription in Nigerian hospitals is high with only about 50% of prescriptions based on clear therapeutic indications. We provide evidence that the country needs to institute a cohesive antimicrobial stewardship intervention program.
Description
Keywords
Antimicrobial stewardship , Nigeria , Point prevalence , Surveillance
Citation
Oduyebo O.O, Olayinka A.T, Iregbu K.C, Versporten A, Goossens H, Nwajiobi-Princewill P.I, Jimoh O, Ige T.O, Aigbe A.I, Ola-Bello O.I, Aboderin A.O. and Ogunsola F.T. (2017). A point prevalence survey of antimicrobial prescribing in four Nigerian Tertiary Hospitals. Ann Trop Pathol, 8:42-6.
URI
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https://ir.unilag.edu.ng/handle/123456789/7155
https://ir.unilag.edu.ng/handle/123456789/7155