Beta-lactamase production in anaerobic bacteria
Date
2010
Authors
Nwaokorie, F.O.
Ogunsola, F.T.
Coker, A.O.
Journal Title
Journal ISSN
Volume Title
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Abstract
Anaerobes occur as major components of bacterial flora of the human skin and mucous membranes. They are responsible
for a variety of serious and life-threatening infections. There is a great concern on the treatment of these infections due to the emergence of antibiotic resistance especially to beta-lactam drugs. Resistance to β-lactam drugs take place in anaerobic microbial species mainly by the production of beta-lactamase and this is frequently associated with therapeutic failures. In this review, the production, genetic determinant, ecological impact and the effects of β-lactamase on therapy is discussed.
Description
Staff publications
Keywords
Anaerobes , Antibiotic resistance , Beta-lactamase production , Research Subject Categories::MEDICINE::Microbiology, immunology, infectious diseases
Citation
Nwaokorie, F.O, Ogunsola, F.T. and Coker, A.O.(2010). Beta-lactamase production in anaerobic bacteria. Reviews in Infection, 1: 172-179.