Emergence of beta-lactamases OXA-10, VEB-1 and CMY in Providencia spp. from Nigeria

Thumbnail Image
Date
2011-05-24
Authors
Aibinu, I.E.
Pfeifer, Y.
Ogunsola, F.T.
Odugbemi, T.
Koenig, W.
Ghebremedhin, B.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Resistance to cephalosporins of the third and fourth generations inEnterobacteriaceae is an increasing problem worldwide. This resist-ance is mainly attributed to the production of extended-spectrumb-lactamases (ESBLs). In Nigeria SHV-, TEM- and CTX-M-typeESBLs have been reported inEnterobacterspp.,Klebsiellaspp. andEscherichia coli.1–3Besides these classical ESBLs, there are variousother plasmid-mediatedb-lactamases that are less common butwhich are regarded as emerging and increasing in frequencyamong theb-lactamase family. Here we report the emergence ofOXA-10, VEB-1 and CMYb-lactamases and mobile genetic elementsin three clinical isolates ofProvidenciaspp. isolated between October2008 and April 2009 in two tertiary hospitals in Nigeria.
Description
Staff publications
Keywords
Antimicrobial resistance , Molecular epidemiology , Esbls , Ampc , Research Subject Categories::MEDICINE::Microbiology, immunology, infectious diseases
Citation
Aibinu, I.E, Pffeifer, Y., Ogunsola, F., Odugbemi, T., Koenig W., and Ghebremedhin, B., (2011). Emergence of beta-lactamases OXA-10, VEB-1 and CMY in Providentia species from Nigeria. Journal of Antimicrobial Chemotherapy, 66 (8): 1931-1932.