Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria
Date
2016-08-30
Authors
Oluyemi, A
Awolola, N
Oyedeji, O.A
Journal Title
Journal ISSN
Volume Title
Publisher
Pan African medical journal
Abstract
Introduction: Colorectal polyps are known precursors of colorectal cancers. The increase in utilization of colonoscopy in Nigeria has meant a rise
in the recently reported incidence of these lesions. The aim of this study is to evaluate the clinicopathological profile of colorectal polyps biopsied
during the inaugural 12 month period of colonoscopy from a private endoscopy suite in Nigeria. Methods: This is a retrospective review of all the
clients who had polyps diagnosed at colonoscopy over a 12 month period (August 2014 –July 2015) at a private endoscopy suite in Lagos, Nigeria.
This analysis of prospectively collected data was performed using clinical information from the endoscopy logs and pathology database system of a
private endoscopy suite based in Lagos, Nigeria. Results: A total of 125 colonoscopies were carried out over the stated period. Of these, 14
individuals had a total of 18 polyps- 4 clients (28.6% of the persons with polyps) had two polyps each. The polyp detection rate was 11.2% while
the polyp per colonoscopy rate was 14.4%. Of these clients, males were 10 in number; giving a male to female ratio of 2.5:1. Their ages ranged
from 37 to 77 years (mean= 57.3 years). The presenting complaint at colonoscopy was hematochezia in 11 (78.6%), new onset constipation in 2
(14.2%) and peri-anal pain in 1 patient (7.1%).The polyps were distributed as follows; 2 (11.1%) in the ascending colon, 1 (5.6%) each in the
transverse and descending colons, 8 (44.4%) in the sigmoid colon, 6(33.3%) located in the rectum. Hence, there was left sided (15 of 18= 83.3%)
preponderance. Pathologically, tubular (adenomatous) polyp with or without low grade dysplastic changes was diagnosed in 6 of the 18 polyps
(giving an adenoma detection rate of 4.8%), 4 (22.2%) were inflammatory polyps, 1 (5.6%) was malignant and another had the rare inflammatory
fibroid polyp. Five (27.8%) of the specimens were reported as non-specific colitis. Conclusion: The study supports the present wisdom that
polyps are clearly less prevalent in our environment when compared to the Western world. The increased prevalence with advancing age, in male
subjects and of left sided lesions, is also in keeping with previous results from our environment. A case is also advanced for the increased
deployment of endoscopy as a tool for the detection of these polyps and ultimately, the reduction of colorectal cancer in our population.
Description
Staff publications
Keywords
Polyps , colonoscopy , adenoma , Nigeria , Research Subject Categories::MEDICINE
Citation
Oluyemi, A., Awolola, N., Oyedeji, A.O. (2016). Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria.Pan African medical journal;24:333 doi:10.11604/pamj.2016.24.333.9434