Postmortem Time Affects Brain, Liver, Kidney and Heart DNA in Male Rat

Simple item page
dc.contributor.authorEbuehi, O.A.T.
dc.contributor.authorMotolani Amode
dc.contributor.authorAyooluwa Balogun
dc.contributor.authorAdenike Fowora
dc.date.accessioned2024-04-24T11:07:30Z
dc.date.available2024-04-24T11:07:30Z
dc.date.issued2015
dc.descriptionSchorlarly Article
dc.description.abstractThe aim of this paper is to evaluate the effect of post-mortem time (0, 24, 48 h) on the integrity of DNA vextracted from the brain, liver, heart and kidney of male albino Sprague –Dawley rats. Random Amplification of Polymorphic DNA–Polymerase Chain Reaction (RAPD-PCR) followed by agarose electrophoresis were used to detect the correlation between DNA integrity and post mortem time. The results of the post-mortem DNA profile showed that DNA degradation was a time dependent process. DNA from brain, as compared to liver and kidney DNA, showed a slower degradation rate and therefore brain could serve as a valuable organ for studying degradation in longer post-mortem time. This study provides the first DNA profile analysis of the postmortem progress of DNA degradation in rats.
dc.identifier.citationEbuehi, O.A.T, Motolani Amode, Ayooluwa Balogun, Adenike Fowora (2015). Postmortem Time Affects Brain, Liver, Kidney and Heart DNA in Male Rat. American Journal of Biochemistry 5(1): 1-5
dc.identifier.other10.5923
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/12734
dc.language.isoen_US
dc.publisherAmerican Journal of Biochemistry
dc.titlePostmortem Time Affects Brain, Liver, Kidney and Heart DNA in Male Rat
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Postmortem Time Affects Brain, Liver, Kidney and Heart.pdf
Size:
289.92 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Biochemistry-Scholarly Publications