Sero-prevalence of Rubella IgG/IgM and Cytomegalovirus IgM among Blood Donors in Lagos State, South-Western Nigeria

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dc.contributor.authorOkekeodogwu, C.C
dc.contributor.authorOsunkalu, V.O
dc.contributor.authorOgbenna, A.A
dc.contributor.authorEgwuatu, F.T
dc.date.accessioned2022-01-31T09:52:25Z
dc.date.available2022-01-31T09:52:25Z
dc.date.issued2021
dc.descriptionScholarly articlesen_US
dc.description.abstractBlood transfusion is usually a lifesaving and therapeutic intervention.However, many preventable errors (especially transfusion transmissible infections) may make this a harmful procedure. Most of these transfusion transmissible infections are caused by viruses. In this study, sero-prevalence of two viruses (rubella and cytomegalovirus) that are usually overlooked in transfusion medicine were determined in Lagos state, Nigeria. This is a cross sectional study which took place at Lagos University Teaching Hospital (LUTH). Consented and eligible blood donors at LUTH were purportedly selected daily until 181 donors were recruited. A structured questionnaire was used as data collection tool. Samples were analyzed in batches using ELISA method. Out of 181 blood donors that participated, male blood donors constituted 87.8% (159) while the females were only 22 (12.2%). The sero-prevalence of Rubella IgG was 87.8% while that of Rubella IgM was 0.0% and anti-CMV IgM was 11.0%. There was a significant association between gender and rubella infection (p=0.03). Routine pre-donation screening for anti-rubella and anti-CMV antibodies might not be cost effective as few donors were sero-negative to these viruses.en_US
dc.identifier.citationOkekeodogwu, C.C., Osunkalu, V.O., Ogbenna, A.A. and Egwuatu, F.T. (2021). Sero-prevalence of Rubella IgG/IgM and Cytomegalovirus IgM among Blood Donors in Lagos State, South-Western NigeriaNigerian Hospital Practice, 27(3-4), 42-46.en_US
dc.identifier.issn1597-7889
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/10860
dc.language.isoenen_US
dc.publisherNigerian Hospital Practiceen_US
dc.subjectRubellaen_US
dc.subjectCMVen_US
dc.subjectIgMen_US
dc.subjectIgGen_US
dc.subjectSero-prevalenceen_US
dc.subjectBlood donorsen_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titleSero-prevalence of Rubella IgG/IgM and Cytomegalovirus IgM among Blood Donors in Lagos State, South-Western Nigeriaen_US
dc.typeArticleen_US
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