Significance of antibiotics resistance amongst clinical bacterial isolates in Lagos

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dc.contributor.authorRotimi, V.O.
dc.contributor.authorOnyenefa, P.I.
dc.contributor.authorBanjo, T.O.
dc.contributor.authorOgunsola, F.T.
dc.contributor.authorAdenuga, A.
dc.date.accessioned2020-01-07T13:52:48Z
dc.date.available2020-01-07T13:52:48Z
dc.date.issued1994
dc.descriptionStaff publicationsen_US
dc.description.abstractIn vitro susceptibility of several strains or six different species or clinical facultative pathogens Involved nosocomial Infections In our hospital was Investigated by a series of disc diffusion, broth dilution and chequerboard titration testing. With disc diffusion method all the test strains, except Streptococcus pyogenes, were resistant to penicillin 46% of the Klebsiellaaerogenes and 73% of the Pseudomonasstarins were generally resistant to cefotax line. The minimum inhibit of y concentration (MIC) of the antibiotics correlated well with the results or the disc diffusion tests. Synergistic effects were demonstrated by various combinations of gentamlein, ampicilin, clindamyclin, coiistin, cefoxitin, and ceftriazone against resistant strains of S. aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella aerogens. Against S. aureus the effect of gentamicin/CLindamyein demonstrated indifference. The need for stringent caution is strongly advocated in the selection of combination therapy for serious infections caused by some hospital bacterial strains particularly in aeutecare units. The clinical microbiologist should be consulted at all times during the precoss of selection of an appropriate combined therapy for expert guidance.en_US
dc.identifier.citationRotimi, V.O, Oyenefa, P.I, Banjo, T.O, Ogunsola, F.T. and Adenuga A. (1994). Significance of antibiotic resistance amongst clinical bacterial isolates in Lagos. W. Afr. J. Med. 13 :81-86.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7307
dc.language.isoenen_US
dc.relation.ispartofseriesW. Afr. J. Med.;Vol.13
dc.subjectAntibioticsen_US
dc.subjectNosocomial infectionsen_US
dc.subjectPenicillin resistanceen_US
dc.subjectAntibiotic synergismen_US
dc.subjectFacultative pathogensen_US
dc.subjectIn vitro susceptibilityen_US
dc.subjectResearch Subject Categories::MEDICINE::Microbiology, immunology, infectious diseasesen_US
dc.titleSignificance of antibiotics resistance amongst clinical bacterial isolates in Lagosen_US
dc.typeArticleen_US
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