Beta-lactamase production in anaerobic bacteria
Loading...
Date
2010
Authors
Nwaokorie, F.O.
Ogunsola, F.T.
Coker, A.O.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Anaerobes occur as major components of bacterial flora of the human skin and mucous membranes. They are responsible
for a variety of serious and life-threatening infections. There is a great concern on the treatment of these infections due to the emergence of antibiotic resistance especially to beta-lactam drugs. Resistance to β-lactam drugs take place in anaerobic microbial species mainly by the production of beta-lactamase and this is frequently associated with therapeutic failures. In this review, the production, genetic determinant, ecological impact and the effects of β-lactamase on therapy is discussed.
Description
Staff publications
Keywords
Anaerobes , Antibiotic resistance , Beta-lactamase production , Research Subject Categories::MEDICINE::Microbiology, immunology, infectious diseases
Citation
Nwaokorie, F.O, Ogunsola, F.T. and Coker, A.O.(2010). Beta-lactamase production in anaerobic bacteria. Reviews in Infection, 1: 172-179.