Extended spectrum beta-lactamase (esbl) in klebsiella pneumoniae isolates from septicaemic children in ibandan, Nigeria
Loading...
Date
2004
Authors
Fashae, K.
Aibinu, I.
Ogunsola, F.T.
Odugbemi, T.
Mee, B.J.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Blood culture was performed on 204 children (aged 1 day-12 years) who presented at the University College Hospital (LJCH) Ibadan, Nigeria, with fever. Eighty-four (41.3%) out of 204 blood cultures were positive. Staphylococcus eureus was the commonest bacterial agent isolated and accounted for (50%j of all the isolates. Klebsiella spp and Salmonella spp each accounted for 21.4% and 10.7% respectively. Other bacterial agents isolated included Escherichia coli, Enterobacter spp. Citrobacter spp. Pseudomonas aeruginosa, Streptococcus Pneumoniae and Serratia spp. Twoof the children died in spite of early use of appropriate antibiotics as determined by antibiotic susceptibility testing. Phenotypic
and molecualr investigation showed extended-spectrum p-lactamase (ESBL) producing K. pneumoniae to be implicated in the death of the children. Several other K. pneumoniae isolates recovered from blood samples expressed ESB Ls and the isolates were shown by pulsed field gel electrophoresis of chromosomal DNA to be genetically unrelated.
Description
Staff publications
Keywords
Klebsiella pneumoniae , septicaemic , Esbl , Blood culture , Research Subject Categories::MEDICINE::Microbiology, immunology, infectious diseases
Citation
Fashae, K., Aibinu, I., Ogunsola F., Odugbemi, T. Mee B.J. (2004). Extended Spectrum beta-Lactamase (ESBL) in Klebsiella Pneumoniae Isolates from Septicaemic Children in Ibadan, Nigeria. Nigerian Journal of Health and Biomedical Sciences, 3: 79-84
URI
https://www.google.com/search?q=Extended+Spectrum+p-Lactamase+(%EF%BF%BDSBL)+in+Klebsiella+Pneumoniae+Isolates+from+Septicaemic+Children+in+Ibadan%2C+Nigeria&oq=Extended+Spectrum+p-Lactamase+(%EF%BF%BDSBL)+in+Klebsiella+Pneumoniae+Isolates+from+Septicaemic+Children+in+Ibadan%2C+Nigeria&aqs=chrome..69i57.591j0j9&sourceid=chrome&ie=UTF-8
https://ir.unilag.edu.ng/handle/123456789/7246
https://ir.unilag.edu.ng/handle/123456789/7246