Extended spectrum beta-lactamase (esbl) in klebsiella pneumoniae isolates from septicaemic children in ibandan, Nigeria

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dc.contributor.authorFashae, K.
dc.contributor.authorAibinu, I.
dc.contributor.authorOgunsola, F.T.
dc.contributor.authorOdugbemi, T.
dc.contributor.authorMee, B.J.
dc.date.accessioned2020-01-06T11:41:15Z
dc.date.available2020-01-06T11:41:15Z
dc.date.issued2004
dc.descriptionStaff publicationsen_US
dc.description.abstractBlood culture was performed on 204 children (aged 1 day-12 years) who presented at the University College Hospital (LJCH) Ibadan, Nigeria, with fever. Eighty-four (41.3%) out of 204 blood cultures were positive. Staphylococcus eureus was the commonest bacterial agent isolated and accounted for (50%j of all the isolates. Klebsiella spp and Salmonella spp each accounted for 21.4% and 10.7% respectively. Other bacterial agents isolated included Escherichia coli, Enterobacter spp. Citrobacter spp. Pseudomonas aeruginosa, Streptococcus Pneumoniae and Serratia spp. Twoof the children died in spite of early use of appropriate antibiotics as determined by antibiotic susceptibility testing. Phenotypic and molecualr investigation showed extended-spectrum p-lactamase (ESBL) producing K. pneumoniae to be implicated in the death of the children. Several other K. pneumoniae isolates recovered from blood samples expressed ESB Ls and the isolates were shown by pulsed field gel electrophoresis of chromosomal DNA to be genetically unrelated.en_US
dc.identifier.citationFashae, K., Aibinu, I., Ogunsola F., Odugbemi, T. Mee B.J. (2004). Extended Spectrum beta-Lactamase (ESBL) in Klebsiella Pneumoniae Isolates from Septicaemic Children in Ibadan, Nigeria. Nigerian Journal of Health and Biomedical Sciences, 3: 79-84en_US
dc.identifier.urihttps://www.google.com/search?q=Extended+Spectrum+p-Lactamase+(%EF%BF%BDSBL)+in+Klebsiella+Pneumoniae+Isolates+from+Septicaemic+Children+in+Ibadan%2C+Nigeria&oq=Extended+Spectrum+p-Lactamase+(%EF%BF%BDSBL)+in+Klebsiella+Pneumoniae+Isolates+from+Septicaemic+Children+in+Ibadan%2C+Nigeria&aqs=chrome..69i57.591j0j9&sourceid=chrome&ie=UTF-8
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7246
dc.language.isoenen_US
dc.relation.ispartofseriesNigerian Journal of Health and Biomedical Sciences;Vol.3
dc.subjectKlebsiella pneumoniaeen_US
dc.subjectsepticaemicen_US
dc.subjectEsblen_US
dc.subjectBlood cultureen_US
dc.subjectResearch Subject Categories::MEDICINE::Microbiology, immunology, infectious diseasesen_US
dc.titleExtended spectrum beta-lactamase (esbl) in klebsiella pneumoniae isolates from septicaemic children in ibandan, Nigeriaen_US
dc.typeArticleen_US
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