Department Of Biochemistry
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Recent Submissions
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Hypoglycaemic and Biochemical Properties of Cnestis Ferruginea
(African Journal of Traditional, Complementary and Alternative Medicines, 2010-05)Increasing incidences of diabetes in Africa has prompted the search for safe and readily available alternative herbal remedies for the treatment of diabetes mellitus. Cnestis ferruginea was extracted with methanol ... -
Sulphadoxine-pyrimethamine alters the antioxidant defense system in blood of rabbit
(Nigerian Journal of Physiological Sciences, 2011-12)Summary: Sulphadoxine-pyrimethamine (SP) despite reported resistance remains an important drug of choice for the treatment and control of malaria in most endemic areas. Exacerbation of intra-erythrocytic oxidative stress ... -
Assessment of liver antioxidant status and mitochondrial membrane composition of Plasmodium berghei-infected mice treated with selected antimalarials
(Acta Biochimica Polonica, 2017-08-09)The present study was aimed at determining and comparing the effects of Artecxin (ART), P – Alaxin (P-ALA), Lonart (LON) and Chloroquine (CQ) on oxidative stress parameters and mitochondrial membrane composition in the ... -
Comparative cytotoxicactivity of selected Nigerian medicinal plant extracts on Ehrlich ascites carcinoma cells
(LASU Journal of Health Sciences, 2019)Background: Nigerian medicinal plants have long been reported to manage cancer and its symptoms. Some of the frequently mentioned plants used for the treatment of cancer reported in Nigerian Ethnobotanical surveys include ... -
Hepaprotective properties of aqueous leaf extract of persea americana, mill (lauraceae) 'avocado' against CCL4-induced damage in rats
(African Journal of Traditional, Complementary and Alternative Medicines, 2013)Background: Natural products from plants have received considerable attention in recent years due to their diverse pharmacological properties, including antioxidants and hepatoprotective activities. The protective effects ... -
Modulation of Erythrocyte Ghost Membrane Ca2+-Pumping ATPase of Healthy and Non-Insulin Dependent Diabetic Humans by alpha, alpha Trehalose-6- Phosphate and Extracts of Carica papaya Linn.
(Nigerian Quarterly Journal of Hospital Medicine, 2017)Background: Although glycosylated Ca - ATPase has not been demonstrated in diabetes mellitus, but it is evident that the enzyme can be significantly glycated under experimental conditions in the presence of appreciable ... -
Anticlastogenic Properties of Methanolic Extract of Cnestis ferruginea Leaves
(Faculty of Applied Sciences, LAUTECH, 2006)The inhibitory activity of methanolic extract of Cnestis ferruginea was investigated in bone marrow cells of mice using micronucleus assay. The mice were fed with the extracts of two different concentrations (100 and ... -
Toxicological and biochemical effects of therapeutic doses of Chloroquine, Artecxin, Lonart and P-Alaxin in P. berghei-infected mice: A comparative study.
(Nigerian Quarterly Journal of Hospital Medicine, 2016-09)Background:Alterations in hematological indices and biochemical parameters are implicated in malaria and many pharmacologic agents used in the treatment of malaria in the tropics. Objective: This study was designed to ... -
Proximate Composition Properties of Different Fish Species Obtained from Lagos, Nigeria
(FoodHACCP.com Publishing, 2011)Proximate body composition is the analysis of water, fat, protein and ash contents of fish. Proximate analysis of three fish species such as Tilapia oreochromis, Pseudolithus senegalensis and Ethmalosa fimbrata were carried ... -
Determination of Heavy Metal Profile in Bottled Water and Sachet Water Samples Obtained From Various Markets in Lagos, Nigeria
(2017-03-27)The provision of safe drinking water is a very important public health priority. Most of the diseases in developing countries are caused by the consumption of contaminated water. The concentrations of six heavy metals and ... -
The Determination of Heavy Metals and Trace Elements in Meats and Meat Prodcts Found In Lagos State
(Journal of Pollution and Public Health, 2018-05-17)Introduction The concentration of heavy metals (Pb, Cr, Cd) and trace elements (Zn, Cu, Mg) were evaluated in a variety of cow meat, goat meat and their organs. Methods The analysis was done using Atomic Absorption ... -
Genotoxic and Biochemica Effects of Consumption of Heavy Metal Contaminated Fish and Its Reversal Using Zinc Supplements in Rats
(Academic Research Publishing Group, 2017)Introduction: Heavy metals such as lead, cadmium, chromium etc are environmental contaminants. They are also known today as human and animal carcinogens. Objectives: The aim of the study was to evaluate the genotoxic and ... -
Effect of consumption of heavy metals contaminated fish (Tilapia Oreachromis) on metabolic parameters in Rabbits
(International Journal of Applied Biology and Pharmaceutical Technology, 2013-08-18)This research paper presents the biochemical effect of the consumption of heavy metals contaminated fish on metabolic parameters in rabbit. Total glucose, cholesterol, protein and levels of alkaline phosphate, ... -
Metal Concentrations in Tissues of Pseudolithus Senegalensis, (Croacker Fish) and Ethmalosa Fimbriata (Bonga Fish) Obtained from Carter Bridge River and Makoko River, Lagos State, Nigeria
(Scientific & Academic Publishing, 2012)This study assessed the concentrations of cadmium, lead, manganese, copper and iron in the tissues of commercially important Croacker fish (Pseudolithus senegalensis) and Bonga fish (Ethmalosa fimbriata) obtained from ... -
Biochemical Assessment of the effects of the consumption of heavy metal contaminated fish (Oreochromics niloticus) on hematological parameters in rat.
(University of Lagos Publication, 2012)The aim of the present investigation was to determine the effect of the consumption of heavy metal contaminated fish (Orechromis niloticus) by rats on heamatological parameters. The experimental group of rats were exposed ... -
Evaluation of Lead, Cadmium and Chromium in Tilapia fish obtained from Makoko and Carter Bridge Rivers in Lagos, Nigeria
(Academic Journals, 2010-11)Most of the fresh water fish consumed in Nigeria comes from the Southern part of the country. The major aim of this study was to evaluate the heavy metal concentrations of Tilapia fish (Tilapia orechromis) of Makoko and ... -
Optimization of Solid State Fermentation of 2-Deoxy-D-Glucose Aspergillus niger Mutant for Improved Cellulase Production
(Nigerian Journal of Biochemistry and Molecular Biology, 2015)Mutation and optimization of solid state fermentation of Aspergillus niger were performed in order to enhance the production of lignocellulolytic enzymes for biotransformation of cellulosic wastes. Spores of the fungus ... -
Short-Term Feeding of Fibre-Enriched Biscuits: Protective Effect against Hepatotoxicity in Diabetic Rats
(Hindawi Publishing Corporation, 2015)The effects of fibre-enriched biscuit on biomarkers associated with hepatotoxicity in diabetic rats were investigated. Diabetes was induced by single intraperitoneal injection of alloxan monohydrate. Treatment lasted for ... -
Modulatory effect of fibre-enriched cake on alloxan-induced diabetic toxicity in rat brain tissues
(Elsevier, 2014-07-24)tDiabetes is a metabolic disorder characterized by hyperglycaemia and it is fast becoming ascourge in sub-Saharan Africa. The nutritional properties of developed fibre-enriched cakeand its protective potential against ... -
INTERPERITONEAL VS ORAL ROUTE OF ALCOHOL ADMINISTRATION,WHICH IS BETTER?
(Global Research Journals, 2013-06)The major problem researchers of alcohol intoxication and its dependence face is the route of administration as animals though good do not mimic the perfect subjects i.e. human beings. This study however compares between ...