Department Of Botany

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https://ir.unilag.edu.ng/handle/123456789/3368
Botany was one of the foundation departments of the Faculty of Science at inception in 1964 (the first Vice-Chancellor, Prof Eni Njoku, being a reputable Botanist of international stature) when the faculty was composed of the School of Biological Sciences and the School of Mathematical and Physical Sciences.

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Browsing Department Of Botany by Author "Adebajo, S.O."

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  • Item
    Open Access
    Co-biomass degradation of fluoranthene by marine-derived fungi; Aspergillus aculeatus and Mucor irregularis: Comprehensive process optimization, enzyme induction and metabolic analyses
    (Elsevier B.V, 2022) Bankole, P.O.; Omoni, V.T.; Mulla, S.I.; Adebajo, S.O.; Adekunle, A.A.
    The application and relevance of marine-derived fungi in the mycoremediation of environment polluted with polycyclic aromatic hydrocarbons (PAHs) is promising whilst limiting envi- ronmental hazards. The present study investigated the fluoranthene degradation efficiency of marine-derived fungal co-culture, Aspergillus aculeatus (AA) and Mucor irregularis (MI) in batch processes (Plackett-Burman experiments) enhanced with the addition of surfactants and solid- state substrates. Further optimization studies done through fractional factorial design revealed that the co-culture exhibited 98.4% fluoranthene degradation capacity after 7 days of incubation. The role played by enzymes was revealed with 93, 85 and 71% induction of laccase, lignin peroxidase and manganese peroxidase respectively during fluoranthene degradation. The Gas Chromatography-Mass Spectrometry analysis revealed the formation of five metabolites; 1,2- dihy- droxyfluoranthene, 9H-fluorene-1,9-dicarboxylic acid, benzene-1,2,4-tricarboxylic acid, benzene- 1,3-dicarboxylic acid and benzoic acid after fluoranthene degradation by AA + MI co-culture which was used in predicting a metabolic pathway. The findings of this study elucidated the promising potentials of marine-derived fungal co-biomass in the eco-friendly remediation of polycyclic aromatic hydrocarbons thus promoting green technology
  • Item
    Open Access
    Novel laccase from Xylaria polymorpha and its efficiency in the biotransformation of pharmaceuticals: Optimization of operational conditions, comparative effect of redox-mediators and toxicity studies
    (Elsevier, 2022) Bankole, P.O.; Omoni, V.T.; Tennison-Omovoh, C.A.; Adebajo, S.O.; Mullae, S.I.; Adekunle, A.A.; Semple, K.T.
    The promising potentials of biocatalytic treatment processes in the removal of micropollutants whilst eliminating health and environmental hazards have attracted great attention in recent years. This current work investigated the biotransformation efficiency of a novel laccase from Xylaria polymorpha (XPL) in comparison with com- mercial laccases from Trametes versicolor (TVL) and Aspergillus sp. (ASL). XPL exhibited better oxidation per- formance (95.7%) on AMX than TVL (92.8%) and ASL (90.5%). Optimization of operational conditions revealed that AMX was best oxidized at pH 5, temperature (30 ◦C), and concentration (1.0 mg L 1). The investigation carried out to determine the effect of redox mediators revealed violuric acid (VLA) as the best redox mediator. The laccase stability experiments elucidated that the oxidation of AMX is time and mediator concentration dependent with ABTS exhibiting highest deactivation of XPL active sites. Two metabolic products; amoxicillin penilloic acid and 5-hydroxy-6-(4-hydroxyphenyl) 3-(1,3-thiazolidin-2-yl)piperazin-2-one of AMX were ob- tained through Liquid Chromatography-Mass Spectrometry (LC-MS) analyses. The toxicity assessments carried out after oxidation of AMX by XPL showed 94% and 97% reduced toxicity on Artemia salina and Aliivibrio fischeri respectively. The study further underscored the efficiency of biocatalytic-mediator technology in the trans- formation of complex micropollutants into less toxic substances in an eco-friendly wa