• Exercise training improves functional walking capacity and activity leve lof Nigerians with chronic biventricular heart failure 

  Ajiboye, O.A.; Anigbogu, C.N.; Ajuluchukwu, J.N.; Jaja, S.I. (Hong Kong Physiotherapy Journal, 2015)

  Background:Exercise training (ET) has been recommended as an adjunctive ther-apy in chronic heart failure but the role of ETin people with biventricular heart failure(BVF) has not been explored in Nigeria.Objective:This ...

• Prediction equations for 6-minute walk distance in apparently healthy Nigerians. Hong Kong Physiotherapy Journal 32, 65- 72. 

  Ajiboye, O.A.; Anigbogu, C.N; Ajuluchukwu, J.N.; Jaja, S.I. (Hong Kong Physiotherapy Journal, 2014)

  AbstractThe aims of this study were to determine the 6-minute walk distance (6MWD),establish prediction equations for the 6MWD in apparently healthy Nigerians, evaluate any ef-fects regarding participant sex, and compare ...

• Chronic Angiotensin II Treatment potentiates HR slowing in Sprague-Dawley Rat during Acute Behavioral Stress 

  Speakman, R.O; Brown, D.R.; Cassis, L.A.; Silcox, D.L.; Anigbogu, C. N.; Randall, D.C.; Hoyt, R.E. (Elsevier B.V., 2013)

  This study examined the effect of2-week infusion of angiotensin-II(Ang-II; 175 ng/kg/min)via minipump in rats (n=7) upon the mean arterial blood pressure (mBP) and heart rate (HR) response to an acute stress as compared ...

• Extended longitudinal analysis of arterial pressure and heart rate control in unanaesthetised rats with type 1 diabetes 

  Anigbogu, C. N.; Speakman, R.O; Silcox, D.L.; Brown, L.V.; Brown, D.R.; Gong, M.C.; Patwardhan, A.R.; Reynolds, R.L.; Karounos, D.G.; Burgess, D.E.; Baldridge, B.R.; Randall, D.C. (Elsevier B.V., 2012)

  Abstract We recorded arterial pressure (BP) and heart rate (HR) in type-1 diabetic rats vs. controls for > 6 months. Diabetic rats (DIAB) were maintained on insulin from the day glucose >250 mg/dl (“Day 0”). Weight was ...

• Chloroquine reduces blood pressure and forearm vascular resistance and increases forearm blood flow in healthy young adults. 

  Anigbogu, C.N.; Adigun, S.A.; Adegunloye, B.J.; Idong, I. (WILEY-BLACKWELL, 1993)

  The effects of chloroquine on resting blood pressure, forearm blood flow (FBF), and forearm vascular resistance (FVR) and on the responses to cold stimulation were studied in healthy young adults. Chloroquine sulphate (800 ...

• Circadian variations in blood pressure, heart rate, and HR-BP Cross-Correlation Coefficient during progression of diabetes mellitus in rats 

  Anigbogu, C.N.; Williams, D.T.; Brown, D.R.; Silcox, D.L.; Speakman, O.R.; Brown, L.C.; Karounos, D.G.; Randall, D.C. (SAGE-Hindawi Access to Research, 2011)

  Circadian changes in cardiovascular function during the progression of diabetes mellitus in the diabetes prone rat (BBDP) (n = 8) were studied. Age-matched diabetes-resistant rats (BBDR) served as controls. BP was recorded ...

• Glucometabolic effects of single and repeated exposure to forced-swimming stress in Sprague-Dawley rats 

  Morakinyo, AO; Iranloye, BO; Ogunsola, OA (2018)

  Objectives. We aimed to evaluate the effects of a single (acute) and repeated (chronic) exposure to forced-swimming stressor on glucose tolerance, insulin sensitivity, lipid profile and glycogen content in male rats. ...

• Dynamics of inflammatory reaction and oxidative stress across maternal serum, placenta and amniotic fluid in laboratory rats and the role played by genistein aglycone 

  Awobajo, FO; Morakinyo, AO; Samuel, TA; Oyelowo, OT; Ogunsola, AO; Onyekwele, PU; Okedina, ME; Ogunbanwo, OO (J. Basic Clin. Physiol. Pharmacol., 2018)

  Background: Genistein was reported to adversely influence fetal development although this is yet to be fully understood as a mechanism. Methods: In this study, pregnant rats were divided into control (Cont.) and genistein ...

• Magnesium upregulates insulin receptor and glucose transporter-4 in streptozotocin-nicotinamide-induced type-2 diabetic rats 

  Morakinyo, AO; Samuel, TA; Adekunbi, DA (2018)

  Objective. We investigated the eff ects of magnesium supplementation on glucose tolerance, insulin sensitivity, oxidative stress as well as the concentration of insulin receptor and glucose transporter-4 in streptozotoci ...

• High-dose perinatal folic-acid supplementation alters insulin sensitivity in Sprague-Dawley rats and diminishes the expression of adiponectin 

  Morakinyo, AO; Samuel, TA; Awobajo, FO; Oludare, GO; Mofolorunso, A (2018)

  The possible intake of folate in excess of the recommended upper levels is a matter of critical importance. This study was conducted to investigate the effects of prenatal and postnatal high folic acid supplementation (FAS) ...

• Role of amygdala kisspeptin in pubertal timing in female rats 

  Adekunbi, DA; Li, XF; Li, S; Adegoke, OA; Iranloye, BO; Morakinyo, AO; Lightman, SL; Taylor, PD; Poston, L; O'Bryne, KT (2017)

  To investigate the mechanism by which maternal obesity disrupts reproductive function in offspring, we examined Kiss1 expression in the hypothalamic arcuate (ARC) and anteroventral periventricular (AVPV) nuclei, and ...

• Anti-fertility effect of calcium channel blockers on male rats: association with oxidative stress. 

  Morakinyo, AO; Iranloye, BO; Daramola, AO; Adegoke, OA (2011)

  Purpose: Calcium ions are vital in many biologic processes including a variety of enzymatic reactions, activation of excitable cells, coupling of electrical activation to cellular secretion, haemostasis, bone metabolism ...

• Insulin receptor and glucose transporter-4 expression in the skeletal muscle of chronically stressed rats 

  Morakinyo, AO; Iranloye, BO; Samuel, TA; Mofolorunso, AM; Adegoke, OA (2016)

  Background: Stress defined as a disruption in the normal homeostatic functions of an organism caused by stressor (a physiological or psychological challenge) is an unavoidable normal component of life. Previous studies ...

• Effects of Zingiber officinale on reproductive functions in male rats 

  Morakinyo, AO; Adeniyi, OS; Arikawe, AP (2009)

  To investigate the effects of Zingiber Officinale on male reproductive functions and study the mechanisms underlying these effects, aqueous extract of Zingiber Officinale were administered orally to two groups of male rats ...

• Evaluation of the abortifacient properties of chloroform extract of Carica papaya L seed in female albino rats 

  Raji, Yinusa; Morakinyo, AO; Akinsomisoye, OS; Oloyo, AK; Esegbue-Peters, PRC; Kunle-Alabi, OT (2006)

  This study was carried out to investigate the impact of oral administration of chloroform extract of Carica papaya seed (CPE) on implantation and pregnancy in female albino rats. The study was divided into three experimental ...

• Effects of methanol extract of Ricinus Communis seed (Linn) on male albino rats 

  Raji, Y; Oloyo, AK; Morakinyo, AO (2006)

  Aim: To investigate the effect of methanol extract of Ricinus communis seed (RCE) on male rats reproductive functions. Methods: Thirty-two male albino rats were divided into four groups. Groups 1, 2 and 3 were gavaged with ...

• Hypotensive effects of the crude extracts of Solanum macrocarpum in Sprague-Dawley rats. 

  Iranloye, BO; Ajayi, GO; Morakinyo, AO; Olajide, AO (2011)

  Hypertension remains a major health problem in terms of treatment, management and control despite recent advances in modern medicine. In the face of the prevalence of this major health problem, lack of accessibility to ...

• Effect of Zingiber officinale (Ginger) on sodium arsenite-induced reproductive toxicity in male rats. Afr. J. Biomed. Res. 13(1): 39-45 

  Morakinyo, AO; Achema, PU; Adegoke, OA (2010)

  Arsenite is a major environmental chemical and a known reproductive toxicant via the depression of spermatogenesis and androgenesis in males. The possibility of sodium arsenite reproductive toxicity been caused by autooxidation ...

• Modulation of antioxidant enzymes and inflammatory cytokines: possible mechanism of antidiabetic effect of ginger extracts. 

  Morakinyo, AO; Akindele, AJ; Ahmed, Z (2011)

  Zingiber officinale is used in African traditional medicine to treat diabetes mellitus. Oxidative stress and inflammation are associated with the pathogenesis of diabetes mellitus and its complications. This investigation ...

• Mineral composition of commonly consumed local foods in Nigeria. 

  Morakinyo, AO; Samuel, TA; Adegoke, OA (2016)

  Appropriate levels of mineral nutrients are required to maintain optimal health as acute imbalances of these minerals can be potentially fatal. Therefore, dietary intake of micronutrients is of public health importance due ...

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