• Angiotensin receptor blockade with Losartan attenuates pressor response to handgrip contraction and enhances natriuresis in salt loaded hypertensive subjects: a quasi-experimental study among Nigerian adults 

  Agbaraolorunpo, F.M.; Sofola, O.A.; Anigbogu, C.N.; Azinge, E.C. (2019)

  Introduction: sympathetic and Renin-Angiotensin-Aldosterone systems play crucial roles in blood pressure response to increased salt intake. This study investigated the effects of angiotensin receptor blocker (ARB) and ...

• Anti-inflammatory and analgesic properties of rhizozome extract of Zingeber Officinale. 

  Raji Y., Udoh U.S., Oluwadara O.O., Akinsomisoye O.S., Awobajo O., Adeshoga K. (African. J. Biomedical Research., 2002)

  The rhizome extract of Zingiber officinale was investigated for anti inflammatory and analgesic properties in albino rats and Swiss mice respectively. The extract (50 and 100 mg/kg b.w) produced significantly (P<0.05) ...

• Reproductive, Hematological and Biochemical profiles of male rats treated with aqueous extract of Spondias Mombin bark. 

  Raji, Y; Gbadegesin, M.A.; Osonuga, O.A.; Rahmat, A.A.; Akinsomisoye, O.S.; Awobajo, F.O.; Kunle-Alabi, O.T.; Esegbue, P.R.C.; Osonuga, I.O.; Lamidi, A.F. (International Journal of Pharmacology, 2006)

  Aqueous extract of Spondias mombin in different dilutions was employed to assess its impact on male reproductive, haematologic and biochemical indices of male albino rats. A single daily intragastric administration of 8.4, ...

• Anti-inflammatory and analgesic properties of rhizozome extract of Zingeber Officinale. 

  Raji Y., Udoh U.S., Oluwadara O.O., Akinsomisoye O.S., Awobajo O., Adeshoga K. (African. J. Biomedical Research., 2002)

  The rhizome extract of Zingiber officinale was investigated for anti inflammatory and analgesic properties in albino rats and Swiss mice respectively. The extract (50 and 100 mg/kg b.w) produced significantly (P<0.05) ...

• Genistein Precipitated Hypothyroidism, Altered Leptin and C-Reactive Protein Synthesis in Pregnant Rats 

  Awobajo, F.O.; Onokpite, B.O.; Ali, Y.M.; Babaleye, T.A.; Uzor, P.O.; Tijani, K.O. (Niger. J. Physiol. Sci., 2015)

  Genistein is an isoflavone constituent of soya. This study examined the mechanism by which genistein produced adverse effects in pregnant laboratory rats. Pregnant rats were divided into control (Con) and genistein (Gen) ...

• Cigarette smoke pollution promotes oxidative stress imbalance and hormonal changes affecting pregnancy outcome in rats 

  Awobajo, F.O.; Oyesola, O.A.; Amah, G.O.; Olakitan, H.A.; Akinyemi, T.M. (J. Afr. Ass. Physiol. Sci., 2015)

  The deleterious effect of cigarette smoke on several health parameters due to pollution of air is of international concern. How these affect all living organisms and their wellbeing is a major research area. The development ...

• Knowledge of the Nutritional and Medicinal Use of Some Vegetables among a Cross Section of Market Women in Two Major Food Markets in Lagos State, South West Nigeria 

  Awobajo, F.O.; Olatunji-Bello, I.I.; Obilade, T.T.; Odugbemi, T.O. (Pakistan Journal of Nutrition, 2010)

  The knowledge of the nutritional and medicinal benefits of some vegetables found around the south west-Nigeria was tested among cross section of market women in Lagos state Nigeria, using questionnaires and coloured ...

• Condition factor, heavy metals and polychlorinated biphenyls (PCBs) in the muscle of fishes in Lagos, Nigeria 

  Oyelowo, O.T.; Awobajo, F.O.; Samuel, T.A.; Sogbesan, Teniola; Fayiga, Adewale; Mofolorunso, Adekunle (Aceh Journal of Animal Science, 2020)

  Fish is an important part of the human diet, is at the top of the aquatic food chain with a high propensity to accumulating contaminants like heavy metals and polychlorinated biphenyls (PCBs) which are toxic to humans. ...

• The immune system cell populations were increased in salt-induced hypertensive rats without an increase in the serum testosterone level 

  Awobajo, F.O.; Okafor, A.E.; Adebayo, H.O. (Physiology International, 2018)

  The consumption of dietary salt has significantly increased globally, especially in the developed countries. High dietary salt intake has been linked to onset and complications in hypertension with a dimorphism tendency. ...

• Fourteen days oral administration of therapeutic dosage of some Antibiotics reduced serum Testosterone in male rats. 

  Awobajo. F.O.; Raji.Y.; Olatunji-Bello.I. I.; Kunle-Alabi.F.T.; Adesanya A.O.; Awobajo T. O. (Nigerian. J of Health and Biomedical Research, 2006)

  Fourteen days oral administration of therapeutic dose of Ampicillin (4mg/100g/day), Cloxacillin (6mg/100g/day) and Tetracycline (12mg/100g/day) separately to healthy adult male albino rats significantly reduced their serum ...

• In vivo and In vitro Reproductive Toxicity Assessment of Ampicillin and Cloxacillin in Mammalian models. 

  Raji Y.; Awobajo F. O.; Kunle-Alabi O.T.; Gbadegesin M. A.; Bolarinwa A. F. (International J. of Pharmacology, 2006)

  Abstract: This study was carried out to investigate the individual impact of ampicillin and cloxacillin on male reproduction using both in vivo and in vitro models. In the in vivo study, forty adult male albino rats divided ...

• Exercise training improves functional walking capacity and activity leve lof Nigerians with chronic biventricular heart failure 

  Ajiboye, O.A.; Anigbogu, C.N.; Ajuluchukwu, J.N.; Jaja, S.I. (Hong Kong Physiotherapy Journal, 2015)

  Background:Exercise training (ET) has been recommended as an adjunctive ther-apy in chronic heart failure but the role of ETin people with biventricular heart failure(BVF) has not been explored in Nigeria.Objective:This ...

• Prediction equations for 6-minute walk distance in apparently healthy Nigerians. Hong Kong Physiotherapy Journal 32, 65- 72. 

  Ajiboye, O.A.; Anigbogu, C.N; Ajuluchukwu, J.N.; Jaja, S.I. (Hong Kong Physiotherapy Journal, 2014)

  AbstractThe aims of this study were to determine the 6-minute walk distance (6MWD),establish prediction equations for the 6MWD in apparently healthy Nigerians, evaluate any ef-fects regarding participant sex, and compare ...

• Chronic Angiotensin II Treatment potentiates HR slowing in Sprague-Dawley Rat during Acute Behavioral Stress 

  Speakman, R.O; Brown, D.R.; Cassis, L.A.; Silcox, D.L.; Anigbogu, C. N.; Randall, D.C.; Hoyt, R.E. (Elsevier B.V., 2013)

  This study examined the effect of2-week infusion of angiotensin-II(Ang-II; 175 ng/kg/min)via minipump in rats (n=7) upon the mean arterial blood pressure (mBP) and heart rate (HR) response to an acute stress as compared ...

• Extended longitudinal analysis of arterial pressure and heart rate control in unanaesthetised rats with type 1 diabetes 

  Anigbogu, C. N.; Speakman, R.O; Silcox, D.L.; Brown, L.V.; Brown, D.R.; Gong, M.C.; Patwardhan, A.R.; Reynolds, R.L.; Karounos, D.G.; Burgess, D.E.; Baldridge, B.R.; Randall, D.C. (Elsevier B.V., 2012)

  Abstract We recorded arterial pressure (BP) and heart rate (HR) in type-1 diabetic rats vs. controls for > 6 months. Diabetic rats (DIAB) were maintained on insulin from the day glucose >250 mg/dl (“Day 0”). Weight was ...

• Chloroquine reduces blood pressure and forearm vascular resistance and increases forearm blood flow in healthy young adults. 

  Anigbogu, C.N.; Adigun, S.A.; Adegunloye, B.J.; Idong, I. (WILEY-BLACKWELL, 1993)

  The effects of chloroquine on resting blood pressure, forearm blood flow (FBF), and forearm vascular resistance (FVR) and on the responses to cold stimulation were studied in healthy young adults. Chloroquine sulphate (800 ...

• Circadian variations in blood pressure, heart rate, and HR-BP Cross-Correlation Coefficient during progression of diabetes mellitus in rats 

  Anigbogu, C.N.; Williams, D.T.; Brown, D.R.; Silcox, D.L.; Speakman, O.R.; Brown, L.C.; Karounos, D.G.; Randall, D.C. (SAGE-Hindawi Access to Research, 2011)

  Circadian changes in cardiovascular function during the progression of diabetes mellitus in the diabetes prone rat (BBDP) (n = 8) were studied. Age-matched diabetes-resistant rats (BBDR) served as controls. BP was recorded ...

• Glucometabolic effects of single and repeated exposure to forced-swimming stress in Sprague-Dawley rats 

  Morakinyo, AO; Iranloye, BO; Ogunsola, OA (2018)

  Objectives. We aimed to evaluate the effects of a single (acute) and repeated (chronic) exposure to forced-swimming stressor on glucose tolerance, insulin sensitivity, lipid profile and glycogen content in male rats. ...

• Dynamics of inflammatory reaction and oxidative stress across maternal serum, placenta and amniotic fluid in laboratory rats and the role played by genistein aglycone 

  Awobajo, FO; Morakinyo, AO; Samuel, TA; Oyelowo, OT; Ogunsola, AO; Onyekwele, PU; Okedina, ME; Ogunbanwo, OO (J. Basic Clin. Physiol. Pharmacol., 2018)

  Background: Genistein was reported to adversely influence fetal development although this is yet to be fully understood as a mechanism. Methods: In this study, pregnant rats were divided into control (Cont.) and genistein ...

• Magnesium upregulates insulin receptor and glucose transporter-4 in streptozotocin-nicotinamide-induced type-2 diabetic rats 

  Morakinyo, AO; Samuel, TA; Adekunbi, DA (2018)

  Objective. We investigated the eff ects of magnesium supplementation on glucose tolerance, insulin sensitivity, oxidative stress as well as the concentration of insulin receptor and glucose transporter-4 in streptozotoci ...

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